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Article

Control of the Inflammatory Macrophage Transcriptional Signature by miR-155.

PloS one - 1 Jan 2016

Jablonski Kyle A, Gaudet Andrew D, Amici Stephanie A, Popovich Phillip G, Guerau-de-Arellano Mireia

Abstract excerpt

Inflammatory M1 spectrum macrophages protect from infection but can cause inflammatory disease and tissue damage, whereas alternatively activated/M2 spectrum macrophages reduce inflammation and promote tissue repair. Modulation of macrophage phenotype may be therapeutically beneficial and requires further understanding of the molecular programs that control macrophage differentiation. A potential mechanism by...

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Identifiers

PMID: 27447824
DOI: 10.1371/journal.pone.0159724
PMCID: PMC4957803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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