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LncRNA MIR155HG regulates M1/M2 macrophage polarization in chronic obstructive pulmonary disease

14 Jun 2019

Abstract excerpt

BACKGROUND: Macrophages play a crucial role in inflammatory diseases, including chronic obstructive pulmonary disease (COPD). MIR155 host gene (MIR155HG), a novel long non-coding RNA (lncRNA), has been recognized as a regulator of macrophage polarization, we thus investigated its role in COPD. METHODS: We used granulocyte-macrophage colony-stimulating factor (GM-CSF) to induce peripheral blood mononuclear cells...

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PMID: 31207576
DOI: 10.1016/j.biopha.2019.109015

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