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Article

Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.

Glia - 1 Nov 2016

Meunier Cécile, Merienne Nicolas, Jollé Charlotte, Déglon Nicole, Pellerin Luc

Abstract excerpt

Huntington's disease (HD) is a fatal neurodegenerative disease in which an early and selective vulnerability of striatal Spiny Projection Neurons is observed. However, several studies have highlighted the implication of glial cells, and in particular astrocytes, in the pathophysiological mechanisms of this disease. A better understanding of the respective contributions of neurons and astrocytes in HD is needed...

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Identifiers

PMID: 27442486
DOI: 10.1002/glia.23022

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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