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Article

Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements.

Cell systems - 1 Aug 2016

Ma Natalie Jing, Isaacs Farren J

Abstract excerpt

Horizontally transferred genetic elements such as viruses and conjugative plasmids move DNA between organisms, increasing genetic diversity but destabilizing engineered biological systems. Here, we used a genomically recoded Escherichia coli strain lacking UAG stop codons and the recognition protein release factor 1 to study how an alternative genetic code influences horizontally transferred genetic element...

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Identifiers

PMID: 27426981
DOI: 10.1016/j.cels.2016.06.009
PMCID: PMC5568630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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