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Article

Expanded Genetic Codes Create New Mutational Routes to Rifampicin Resistance in Escherichia coli.

Molecular biology and evolution - 1 Aug 2016

Hammerling Michael J, Gollihar Jimmy, Mortensen Catherine, Alnahhas Razan N, Ellington Andrew D, Barrick Jeffrey E

Abstract excerpt

Until recently, evolutionary questions surrounding the nature of the genetic code have been mostly limited to the realm of conjecture, modeling, and simulation due to the difficulty of altering this fundamental property of living organisms. Concerted genome and protein engineering efforts now make it possible to experimentally study the impact of alternative genetic codes on the evolution of biological systems....

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Identifiers

PMID: 27189550
DOI: 10.1093/molbev/msw094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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