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Stop codon recoding is widespread in diverse phage lineages and has the potential to regulate translation of late stage and lytic genes

2021-08-26

Abstract excerpt

The genetic code is a highly conserved feature of life. However, some “alternative” genetic codes use reassigned stop codons to code for amino acids. Here, we survey stop codon recoding across bacteriophages (phages) in human and animal gut microbiomes. We find that stop codon recoding has evolved in diverse clades of phages predicted to infect hosts that use the standard code. We provide evidence for an evolution...

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Literature Corpus work
e0f7d939-4ab6-5cdf-9fc4-315519e56080
DOI
10.1101/2021.08.26.457843
Open publication

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Stop codon recoding is widespread in diverse phage lineages and has the potential to regulate translation of late stage and lytic genesDOI 10.1101/2021.08.26.457843
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