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Article

Stop codon reassignments in the wild.

Science (New York, N.Y.) - 23 May 2014

Ivanova Natalia N, Schwientek Patrick, Tripp H James, Rinke Christian, Pati Amrita, Huntemann Marcel, Visel Axel, Woyke Tanja, Kyrpides Nikos C, Rubin Edward M

Abstract excerpt

The canonical genetic code is assumed to be deeply conserved across all domains of life with very few exceptions. By scanning 5.6 trillion base pairs of metagenomic data for stop codon reassignment events, we detected recoding in a substantial fraction of the >1700 environmental samples examined. We observed extensive opal and amber stop codon reassignments in bacteriophages and of opal in bacteria. Our data...

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PMID: 24855270
DOI: 10.1126/science.1250691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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