Challenges in identifying cancer genes by analysis of exome sequencing data.

Abstract excerpt

Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysis methods to specifically recover known cancer genes. While some cancer genes are identified by analysis of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Databases, Genetic
• Share to Exome
• Share to High-Throughput Nucleotide Sequencing