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Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features.

Scientific reports - 27 Jan 2017

Lanzós Andrés, Carlevaro-Fita Joana, Mularoni Loris, Reverter Ferran, Palumbo Emilio, Guigó Roderic, Johnson Rory

Abstract excerpt

Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such "driver lncRNAs" are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. We here present a different approach for driver lncRNA discovery using mutational patterns in tumour...

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PMID: 28128360
DOI: 10.1038/srep41544
PMCID: PMC5269722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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