Article
Whole-exome sequencing reveals recurrent somatic mutation networks in cancer.
Cancer letters - 1 Nov 2013
Liu Xiaoping, Wang Jiguang, Chen Luonan
Abstract excerpt
The second-generation sequencing technologies have been extensively used to reveal the mechanism of tumorigenesis and find critical genes in cancer progression that can be potential targets of clinic treatment. Exome is a part of genome formed by exons which are the protein-coding portions of genes. The whole-exome sequencing information can reflect the mutations of the protein-coding region in the genome and...
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