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Article

Research to Practice Implications of High-Risk Genotypes for Beryllium Sensitization and Disease.

Journal of occupational and environmental medicine - 1 Sept 2016

Kreiss Kathleen, Fechter-Leggett Ethan D, McCanlies Erin C, Schuler Christine R, Weston Ainsley

Abstract excerpt

OBJECTIVE: Beryllium workers may better understand their genetic susceptibility to chronic beryllium disease (CBD) expressed as population-based prevalence, rather than odds ratios from case-control studies. METHODS: We calculated CBD prevalences from allele-specific DNA sequences of 853 workers for Human Leukocyte Antigen (HLA)-DPB1 genotypes and groups characterized by number of E69-containing alleles and by...

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PMID: 27414009
DOI: 10.1097/JOM.0000000000000805
PMCID: PMC5339739

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