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Article

Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta-analysis.

Journal of cancer research and therapeutics - 1 Dec 2016

Lin Li, Chen Guang-Yong, Xu Chun-Wei, Wang Hai-Yan, Wu Yong-Fang, Fang Mei-Yu

Abstract excerpt

OBJECTIVE: The aim of this meta-analysis is to evaluate the distribution pattern of KRAS and BRAF mutations in colorectal cancer. MATERIALS AND METHODS: The database was searched without language restrictions. Meta-analyses were conducted using the STATA software. We calculated the odds ratio (OR) and its 95% confidence interval (95% CI) to estimate the distribution of and correlation between KRAS and BRAF...

Topics

Colorectal Neoplasms
CpG Islands
DNA Methylation
Gene Expression Regulation, Neoplastic
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Microsatellite Instability
Mutation
Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proto-Oncogene Proteins B-raf

Publication Bias

ras Proteins

Source

Identifiers

PMID: 28230016
DOI: 10.4103/0973-1482.200601

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28230016-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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