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Article

A tug-of-war between tolerance and rejection - New evidence for 3'UTR HLA-G haplotypes influence in recurrent pregnancy loss.

Human immunology - 1 Oct 2016

Michita Rafael Tomoya, Zambra Francis Maria Báo, Fraga Lucas Rosa, Sanseverino Maria Teresa Vieira, Callegari-Jacques Sidia Maria, Vianna Priscila, Chies José Artur Bogo

Abstract excerpt

HLA-G is a molecule essential to the maintenance of the maternal-fetal interface tolerance, thus contributing to a healthy pregnancy. Here we investigate the role of HLA-G single nucleotide polymorphisms (SNPs) and whether a specific HLA-G haplotype influence or not recurrent pregnancy loss (RPL) risk. A total of 296 DNA samples from RPL (N=140) and controls (N=156) were evaluated. The HLA-G 3'UTR region was...

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Identifiers

PMID: 27397898
DOI: 10.1016/j.humimm.2016.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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