Article
Association between novel HLA-G genotypes and risk of recurrent miscarriages: a case-control study in a South Indian population.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Oct 2008
Suryanarayana Venkata, Rao Lakshmi, Kanakavalli Murthy, Padmalatha Venkata, Raseswari Turalpati, Deenadayal Mamata, Singh Lalji
Abstract excerpt
HLA-G is a nonclassical histocompatibility complex member associated with fetal tolerance of the mother observed during pregnancy. Despite its being a less polymorphic gene, a number of studies have evaluated the role of HLA-G gene polymorphisms on the risk of pregnancy-related complications. A 14-bp deletion polymorphism in exon 8 (3'UTR) was known to influence the levels of soluble HLA-G, differential splicing...
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