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Article

Association of HLA-G alleles and 3' UTR 14 bp haplotypes with recurrent miscarriage in Brazilian couples.

Human immunology - 1 Jun 2011

Vargas Rafael Gustavo, Sarturi Paulo Roberto, Mattar Sibelle Botogosque, Bompeixe Eni Piccioni, Silva Joandrei dos Santos, Pirri Alessandro, Bicalho Maria da Graça

Abstract excerpt

Human leukocyte antigen (HLA)-G expression is restricted, expressed on trophoblast, with a major role in fetus acceptance. In addition to the 46 HLA-G alleles, the presence or absence of a 14 bp polymorphism located in the 3' UTR contributes to gene polymorphism that may influence both HLA-G mRNA stability and HLA-G isoform's splicing and consequently could play an immunomodulatory function in pregnancy. To...

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Identifiers

PMID: 21354454
DOI: 10.1016/j.humimm.2011.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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