Article
Association of genetic variants in the 3'UTR of HLA-G with Recurrent Pregnancy Loss.
Human immunology - 1 Oct 2016
Amodio Giada, Canti Valentina, Maggio Luana, Rosa Susanna, Castiglioni Maria Teresa, Rovere-Querini Patrizia, Gregori Silvia
Abstract excerpt
Human Leukocyte Antigen (HLA)-G is involved in reprogramming immune responses at fetal-maternal interface during pregnancy. We evaluated the genetic diversity of the 3' Un-Translated Region (UTR) of HLA-G, previously associated with HLA-G mRNA post-transcriptional regulation, in women with unexplained Recurrent Pregnancy Loss (RPL), with 2 pregnancy losses (RPL-2, n=28), or 3 or more pregnancy losses (RPL-3,...
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