Article
Role of the HLA-G regulatory region polymorphisms in idiopathic recurrent spontaneous abortions (RSA).
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Aug 2023
Marik Binata, Nomani Khusru, Agarwal Nutan, Dadhwal Vatsla, Sharma Arundhati
Abstract excerpt
PROBLEM: HLA-G polymorphisms have a functional impact on its expression and may cause a breakdown of maternal tolerance towards the semi-allogenic fetus, resulting in recurrent spontaneous abortions (RSA). This study reports on the association of HLA-G regulatory region polymorphisms with idiopathic RSA. METHODS: Seventy-five couples with ≥2 spontaneous abortions were recruited in comparison to 75 healthy couples...
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