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Article

Ralationship between polymorphisms and diplotypes of HLA-G 3'UTR and fetuses with abnormal chromosomes or unexplained pregnancy loss (UPL).

Human genomics - 17 Nov 2024

Xu Danping, Zhu Yiyang, Wang Jun, Guan Heqin, Shen Xiuzhen

Abstract excerpt

OBJECTIVES: Human leukocyte antigen G (HLA-G) plays a crucial role in pregnancy. Pregnancy loss (PL) is caused by a variety of causes, such as fetal chromosomal abnormalities, maternal hypertension and diabetes, immune causes, spontaneous immune diseases, infections, unknown causes, etc. This study reports on the association of fetal HLA-G 3'UTR polymorphisms and diplotypes with chromosomally abnormal fetuses...

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Identifiers

PMID: 39551809
DOI: 10.1186/s40246-024-00695-5
PMCID: PMC11572094

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