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Article

Lower frequency of the HLA-G UTR-4 haplotype in women with unexplained recurrent miscarriage.

Journal of reproductive immunology - 1 Apr 2018

Meuleman T, Drabbels J, van Lith J M M, Dekkers O M, Rozemuller E, Cretu-Stancu M, Claas F H J, Bloemenkamp K W M, Eikmans M

Abstract excerpt

HLA-G expressed by trophoblasts at the fetal-maternal interface and its soluble form have immunomodulatory effects. HLA-G expression depends on the combination of DNA polymorphisms. We hypothesized that combinations of specific single nucleotide polymorphisms (SNPs) in the 3'untranslated region (3'UTR) of HLA-G play a role in unexplained recurrent miscarriage. In a case control design, 100 cases with at least...

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Identifiers

PMID: 29481987
DOI: 10.1016/j.jri.2018.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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