Article
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq.
Nature communications - 7 Jul 2016
Weissbein Uri, Schachter Maya, Egli Dieter, Benvenisty Nissim
Abstract excerpt
Genomic instability has profound effects on cellular phenotypes. Studies have shown that pluripotent cells with abnormal karyotypes may grow faster, differentiate less and become more resistance to apoptosis. Previously, we showed that microarray gene expression profiles can be utilized for the analysis of chromosomal aberrations by comparing gene expression levels between normal and aneuploid samples. Here we...
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