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Single-nucleotide polymorphism array karyotyping in clinical practice: where, when, and how?

Seminars in oncology - 1 Feb 2012

Sato-Otsubo Aiko, Sanada Masashi, Ogawa Seishi

Abstract excerpt

Single-nucleotide polymorphism array (SNP-A) karyotyping is a new technology that has enabled genome-wide detection of genetic lesions in human cancers, including hematopoietic neoplasms. Taking advantage of very large numbers of allele-specific probes synthesized on microarrays at high density, copy number alterations as well as allelic imbalances can be sensitively detected in a genome-wide manner at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22289488
DOI: 10.1053/j.seminoncol.2011.11.010

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