Article
Tumor Biology Rather Than Surgical Technique Dictates Prognosis in Colorectal Cancer Liver Metastases.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Nov 2016
Margonis Georgios Antonios, Sasaki Kazunari, Kim Yuhree, Samaha Mario, Buettner Stefan, Amini Neda, Antoniou Efstathios, Pawlik Timothy M
Abstract excerpt
INTRODUCTION: The interplay of tumor biology and surgical margin status after resection for colorectal liver metastasis (CRLM) remains controversial. Consequently, we sought to determine the impact of surgical margin status on overall survival (OS) stratified by KRAS mutational status. MATERIALS AND METHODS: Four hundred eighty-five patients with known KRAS mutational status were identified. Clinicopathologic and...
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