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Article

Does KRAS mutation status impact the risk of local recurrence after R1 vascular resection for colorectal liver metastasis? An observational cohort study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 May 2020

Procopio Fabio, Viganò Luca, Cimino Matteo, Donadon Matteo, Del Fabbro Daniele, Torzilli Guido

Abstract excerpt

INTRODUCTION: R0 margin is the standard in the surgical treatment of colorectal liver metastases (CLM). Recently R1 surgery, at least that enabling CLM vessel-detachment (R1vasc), seems comparable to R0. As a possible background of that biologic factors could play some role. Among them, KRAS has been investigated in the present study. METHODS: Patients who underwent curative surgery for CLM between 2008 and 2016...

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Identifiers

PMID: 31839435
DOI: 10.1016/j.ejso.2019.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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