Improved Survival over Time After Resection of Colorectal Liver Metastases and Clinical Impact of Multigene Alteration Testing in Patients with Metastatic Colorectal Cancer.

doi:10.1007/s11605-021-05110-1

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Article

Improved Survival over Time After Resection of Colorectal Liver Metastases and Clinical Impact of Multigene Alteration Testing in Patients with Metastatic Colorectal Cancer.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Mar 2022

Kawaguchi Yoshikuni, Kopetz Scott, Panettieri Elena, Hwang Hyunsoo, Wang Xuemei, Cao Hop S Tran, Tzeng Ching-Wei D, Chun Yun Shin, Aloia Thomas A, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: The past 20 years have seen advances in colorectal cancer management. We sought to determine whether survival in patients undergoing resection of colorectal liver metastases (CLM) has improved in association with three landmark advances: introduction of irinotecan- and/or oxaliplatin-containing regimens, molecular targeted therapy, and multigene alteration testing. METHODS: Patients undergoing CLM...

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PMID: 34506029
DOI: 10.1007/s11605-021-05110-1

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