Critical appraisal of surgical margins according to KRAS status in liver resection for colorectal liver metastases: Should surgical strategy be influenced by tumor biology?

doi:10.1016/j.surg.2024.02.008

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Critical appraisal of surgical margins according to KRAS status in liver resection for colorectal liver metastases: Should surgical strategy be influenced by tumor biology?

Surgery - 1 Jul 2024

Rhaiem Rami, Duramé Adrien, Primavesi Florian, Dorcaratto Dimitri, Syn Nicholas, Rodríguez Ángela de la Hoz, Dupré Aurélien, Piardi Tullio, Fernández Gerardo Blanco, Villaverde Arancha Prada, Rodríguez Sanjuán Juan C, Santiago Roberto Fernández, Fernández-Moreno María-Carmen, Ferret Georgina, Ben Santiago López, Suárez Muñoz Miguel Á, Perez-Alonso Alejandro J, Koh Ye-Xin, Jones Robert, Martín-Pérez Elena, Kianmanesh Reza, Di Martino Marcello

Abstract excerpt

BACKGROUND: KRAS mutation is a negative prognostic factor for colorectal liver metastases. Several studies have investigated the resection margins according to KRAS status, with conflicting results. The aim of the study was to assess the oncologic outcomes of R0 and R1 resections for colorectal liver metastases according to KRAS status. METHODS: All patients who underwent resection for colorectal liver metastases...

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PMID: 38519408
DOI: 10.1016/j.surg.2024.02.008

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Critical appraisal of surgical margins according to KRAS status in liver resection for colorectal liver metastases: Should surgical strategy be influenced by tumor biology?PMID 38519408Read ↗

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