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Article

RAS Mutation Predicts Positive Resection Margins and Narrower Resection Margins in Patients Undergoing Resection of Colorectal Liver Metastases.

Annals of surgical oncology - 1 Aug 2016

Brudvik Kristoffer Watten, Mise Yoshihiro, Chung Michael Hsiang, Chun Yun Shin, Kopetz Scott E, Passot Guillaume, Conrad Claudius, Maru Dipen M, Aloia Thomas A, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: In patients undergoing resection of colorectal liver metastases (CLM), resection margin status is a significant predictor of survival, particularly in patients with suboptimal response to preoperative therapy. RAS mutations have been linked to more invasive and migratory tumor biology and poor response to modern chemotherapy. OBJECTIVE: The aim of this study was to evaluate the relationship between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27016292
DOI: 10.1245/s10434-016-5187-2
PMCID: PMC5527830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RAS Mutation Predicts Positive Resection Margins and Narrower Resection Margins in Patients Undergoing Resection of Colorectal Liver Metastases.PMID 27016292Read ↗

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