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Article

Neither Surgical Margin Status nor Somatic Mutation Predicts Local Recurrence After R0-intent Resection for Colorectal Liver Metastases.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Apr 2022

Nishioka Yujiro, Paez-Arango Natalia, Boettcher Federico Oppliger, Kawaguchi Yoshikuni, Newhook Timothy E, Chun Yun Shin, Tzeng Ching-Wei D, Tran Cao Hop S, Lee Jeffrey E, Vreeland Timothy J, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: We evaluated the associations of surgical margin status and somatic mutations with the incidence of local recurrence (LR) and oncologic outcomes in patients undergoing R0-intent (microscopically negative margin) resection of colorectal liver metastases (CLM). METHODS: Patients with CLM who underwent initial R0-intent resection and analysis of tumor tissue using next-generation sequencing during...

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Colorectal Neoplasms
Hepatectomy
Liver Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

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PMID: 34725784
DOI: 10.1007/s11605-021-05173-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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