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Article

CYP2C19 but not CYP2B6, CYP3A4, CYP3A5, ABCB1, PON1 or P2Y12 genetic polymorphism impacts antiplatelet response after clopidogrel in Koreans.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2017

Zhang Hong-Zhe, Kim Moo Hyun, Guo Long-Zhe, Serebruany Victor

Abstract excerpt

Clopidogrel response variability (CRV) is well documented, and may affect clinical outcomes. Impact of genetic polymorphisms is important for assessing and predicting CRV. The extensive evidence indicates the importance of CYP2C19 variants in reducing efficacy of clopidogrel. This study defined the impact of numerous genetic polymorphisms on CRV before and after percutaneous coronary interventions (PCI)...

Read the complete abstract on PubMed

Topics

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to Clopidogrel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to PON1 gene

Share to Platelet Aggregation Inhibitors

Share to Polymorphism, Single Nucleotide

Share to Ticlopidine

Source

Identifiers

PMID: 27380588
DOI: 10.1097/MBC.0000000000000536

Genes

ABCB1
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CYP2C19 but not CYP2B6, CYP3A4, CYP3A5, ABCB1, PON1 or P2Y12 genetic polymorphism impacts antiplatelet response after clopidogrel in Koreans.PMID 27380588Read ↗

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