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Article

Genotyping of six clopidogrel-metabolizing enzyme polymorphisms has a minor role in the assessment of platelet reactivity in patients with acute coronary syndrome.

Anatolian journal of cardiology - 1 Apr 2017

García-Lagunar María Henar, Consuegra-Sánchez Luciano, Conesa-Zamora Pablo, Ruiz-Cosano Javier, Soria-Arcos Federico, García de Guadiana Luis, Vivar Pedro Cano, Castillo-Moreno Juan Antonio, Melgarejo-Moreno Antonio

Abstract excerpt

OBJECTIVE: To evaluate the contribution of six polymorphisms to the platelet reactivity in patients with acute coronary syndrome (ACS) treated with clopidogrel. METHODS: Cross-sectional study of 278 consecutive patients with ACS. Detailed clinical information for each patient was collected and genotypes (CYP2C9*2, CYP2C9*3, CYP2C19*2, CYP2C19*17, CYP3A4*1B, and PON1-Q192R) were evaluated with TaqMan® and KASPar®...

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Identifiers

PMID: 28179614
DOI: 10.14744/AnatolJCardiol.2016.7390
PMCID: PMC5469111

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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