Article
Association of cytochrome P450 2C19*2 polymorphism with clopidogrel response variability and cardiovascular events in Koreans treated with drug-eluting stents.
Heart (British Cardiac Society) - 1 Jan 2012
Oh Il-Young, Park Kyung Woo, Kang Si-Hyuk, Park Jin Joo, Na Sang-Hoon, Kang Hyun-Jae, Koo Bon-Kwon, Jeong Young-Hoon, Hwang Jin-Yong, Kwak Choong Hwan, Park Yongwhi, Hwang Seok-Jae, Ko Young-Guk, Shin Dong Jik, Jang Yangsoo, Kim Hyo-Soo
Abstract excerpt
BACKGROUND: Although East Asians carry the cytochrome P450 (CYP) 2C19*2 allele more frequently than do Caucasians, the impact of the CYP2C19*2 allele on clopidogrel pharmacodynamics and clinical outcomes is unknown. OBJECTIVE: To evaluate the effect of CYP2C19 variants on clopidogrel pharmacodyna...
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