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Article

Effects of genetic variants on platelet reactivity and one-year clinical outcomes after percutaneous coronary intervention: A prospective multicentre registry study.

Scientific reports - 19 Jan 2018

Joo Hyung Joon, Ahn Sung Gyun, Park Jae Hyoung, Park Ji Young, Hong Soon Jun, Kim Seok-Yeon, Choi WoongGil, Gwon HyeonCheol, Lim Young-Hyo, Kim Weon, Kang Woong Chol, Cho Yun-Hyeong, Kim Yong Hoon, Yoon JungHan, Shin WonYong, Hong Myeong-Ki, Garg Scot, Jang Yangsoo, Lim Do-Sun

Abstract excerpt

Clopidogrel is the mainstay for antiplatelet treatment after percutaneous coronary intervention (PCI). The relationship of platelet reactivity and genetic polymorphism with clinical outcomes with newer-generation drug-eluting stents is unclear. We analysed 4,587 patients for the most powerful single-nucleotide polymorphisms (CYP2C19, CYP2C9, ABCB1, PON1, and P2Y12) related to on-treatment platelet reactivity...

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Share to Aryldialkylphosphatase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29352151
DOI: 10.1038/s41598-017-18134-y
PMCID: PMC5775197

Genes

ABCB1
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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