Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unique CD8+ T Cell-Mediated Immune Responses Primed in the Liver.

Transplantation - 1 Sept 2016

Zimmerer Jason M, Horne Phillip H, Fisher Mason G, Pham Thomas A, Lunsford Keri E, Ringwald Bryce A, Avila Christina L, Bumgardner Ginny L

Abstract excerpt

BACKGROUND: The liver immune environment is tightly regulated to balance immune activation with immune tolerance. Understanding the dominant immune pathways initiated in the liver is important because the liver is a site for cell transplantation, such as for islet and hepatocyte transplantation. The purpose of this study is to examine the consequences of alloimmune stimulation when allogeneic cells are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Microenvironment
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Rejection

Share to Graft Survival

Share to Immunity, Cellular

Share to Immunity, Humoral

Share to Liver Transplantation

Share to Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 27379551
DOI: 10.1097/TP.0000000000001290
PMCID: PMC4935926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unique CD8+ T Cell-Mediated Immune Responses Primed in the Liver.PMID 27379551Read ↗

Cytotoxic effector function of CD4-independent, CD8(+) T cells is mediated by TNF-α/TNFR.Semantic proximity Read ↗

Antigen-Specific Immunotherapy for Treatment of Autoimmune Liver Diseases.Semantic proximity Read ↗

Strategies for Deliberate Induction of Immune Tolerance in Liver Transplantation: From Preclinical Models to Clinical Application.Semantic proximity Read ↗

Induction of local immunosuppression in allogeneic cell transplantation by cell-type-specific expression of PD-L1 and CTLA4IgSemantic proximity Read ↗

Liver transplantation in the mouse: Insights into liver immunobiology, tissue injury, and allograft toleranceSemantic proximity Read ↗

Liver transplant rejection features memory cell priming, spatially differentiated networks and novel drug targetsSemantic proximity Read ↗

Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2low Bimhigh phenotype, poor CTL function and cell death.Semantic proximity Read ↗

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological NicheSemantic proximity Read ↗

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.Semantic proximity Read ↗

Unique Aspects of Rejection and Tolerance in Liver TransplantationSemantic proximity Read ↗

Systemic transmigration of allosensitizing donor dendritic cells to host secondary lymphoid organs after rat liver transplantation.Semantic proximity Read ↗

Liver sinusoidal endothelial cells: a new type of organ-resident antigen-presenting cell.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.