Article
Systemic transmigration of allosensitizing donor dendritic cells to host secondary lymphoid organs after rat liver transplantation.
Hepatology (Baltimore, Md.) - 1 Apr 2008
Ueta Hisashi, Shi Changde, Miyanari Nobutomo, Xu Xue-Dong, Zhou Shu, Yamashita Masaki, Ezaki Taichi, Matsuno Kenjiro
Abstract excerpt
UNLABELLED: Donor dendritic cell (DC) migration and allosensitization in host secondary lymphoid organs after liver transplantation are ill defined. We used rat models to investigate graft-derived cells and intrahost allosensitization. Liver transplantation induced diffuse blood-borne migration of donor major histocompatibility class II antigen-positive (MHCII(+)) cells and MHCI(+) cells from the graft to host...
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