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Article

Naïve CD8 T cell activation by liver bone marrow-derived cells leads to a "neglected" IL-2low Bimhigh phenotype, poor CTL function and cell death.

Journal of hepatology - 1 Oct 2012

Holz Lauren E, Benseler Volker, Vo Michelle, McGuffog Claire, Van Rooijen Nico, McCaughan Geoffrey W, Bowen David G, Bertolino Patrick

Abstract excerpt

BACKGROUND & AIMS: The occurrence of primary CD8 T cell activation within the liver, unique among the non-lymphoid organs, is now well accepted. However, the outcome of intrahepatic T cell activation remains controversial. We have previously reported that activation initiated by hepatocytes resul...

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PMID: 22659099
DOI: 10.1016/j.jhep.2012.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22659099-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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