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Liver transplantation in the mouse: Insights into liver immunobiology, tissue injury, and allograft tolerance

28 Dec 2015

Abstract excerpt

The surgically demanding mouse orthotopic liver transplant model was first described in 1991. It has proved to be a powerful research tool for the investigation of liver biology, tissue injury, the regulation of alloimmunity and tolerance induction, and the pathogenesis of specific liver diseases. Liver transplantation in mice has unique advantages over transplantation of the liver in larger species, such as the...

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PMID: 26709949
DOI: 10.1002/lt.24394

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