Article
Antigen-Specific Immunotherapy for Treatment of Autoimmune Liver Diseases.
Frontiers in immunology - 1 Jan 2020
Richardson Naomi, Ng Sky T H, Wraith David C
Abstract excerpt
The liver is a critical organ in controlling immune tolerance. In particular, it is now clear that targeting antigens for presentation by antigen presenting cells in the liver can induce immune tolerance to either autoantigens from the liver itself or tissues outside of the liver. Here we review immune mechanisms active within the liver that contribute both to the control of infectious diseases and tolerance to...
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