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Article

The α-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals.

Pharmacogenetics and genomics - 1 Sept 2016

Shorter Daryl, Nielsen David A, Hamon Sara C, Nielsen Ellen M, Kosten Thomas R, Newton Thomas F, De La Garza Richard

Abstract excerpt

OBJECTIVES: We examined whether a functional variant of the ADRA1A gene moderated cocaine-induced subjective effects in a group of cocaine-dependent individuals. METHODS: This study was a within-participant, double-blind, placebo-controlled inpatient human laboratory evaluation of 65 nontreatment-seeking, cocaine-dependent [Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV)] individuals aged...

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Source

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Identifiers

PMID: 27379509
DOI: 10.1097/FPC.0000000000000234
PMCID: PMC4970930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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