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Article

Promoter region variant C-824T in the TH gene modulates the subjective effects of cocaine.

The American journal on addictions - 1 Sept 2023

Bolin Peter K, Nielsen Ellen M, Nielsen David A, De La Garza Richard

Abstract excerpt

BACKGROUND AND OBJECTIVES: This study examined how a promoter variant of TH (rs10770141) affects subjective effects of cocaine in 65 nontreatment-seeking individuals with cocaine dependence. METHODS: Participants received cocaine/saline intravenously, and TH genotypes were evaluated. RESULTS: Homozygous individuals for the minor T allele reported greater "good" and "bad" subjective effects to cocaine than those...

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Identifiers

PMID: 37337750
DOI: 10.1111/ajad.13444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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