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Article

Gene x abstinence effects on drug cue reactivity in addiction: multimodal evidence.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Jun 2013

Moeller Scott J, Parvaz Muhammad A, Shumay Elena, Beebe-Wang Nicasia, Konova Anna B, Alia-Klein Nelly, Volkow Nora D, Goldstein Rita Z

Abstract excerpt

Functional polymorphisms in the dopamine transporter gene (DAT1 or SLC6A3) modulate responsiveness to salient stimuli, such that carriers of one 9R-allele of DAT1 (compared with homozygote carriers of the 10R-allele) show heightened reactivity to drug-related reinforcement in addiction. Here, using multimodal neuroimaging and behavioral dependent variables in 73 human cocaine-addicted individuals and 47 healthy...

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Source

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Identifiers

PMID: 23761898
DOI: 10.1523/JNEUROSCI.0695-13.2013
PMCID: PMC3682385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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