Article
Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2017
Coleman Jonathan R I, Lester Kathryn J, Roberts Susanna, Keers Robert, Lee Sang Hyuck, De Jong Simone, Gaspar Héléna, Teismann Tobias, Wannemüller André, Schneider Silvia, Jöhren Peter, Margraf Jürgen, Breen Gerome, Eley Thalia C
Abstract excerpt
OBJECTIVES: Exposure-based cognitive behavioural therapy (eCBT) is an effective treatment for anxiety disorders. Response varies between individuals. Gene expression integrates genetic and environmental influences. We analysed the effect of gene expression and genetic markers separately and together on treatment response. METHODS: Adult participants (n ≤ 181) diagnosed with panic disorder or a specific phobia...
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