Article
Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.
The British journal of psychiatry : the journal of mental science - 1 Sept 2016
Coleman Jonathan R I, Lester Kathryn J, Keers Robert, Roberts Susanna, Curtis Charles, Arendt Kristian, Bögels Susan, Cooper Peter, Creswell Cathy, Dalgleish Tim, Hartman Catharina A, Heiervang Einar R, Hötzel Katrin, Hudson Jennifer L, In-Albon Tina, Lavallee Kristen, Lyneham Heidi J, Marin Carla E, Meiser-Stedman Richard, Morris Talia, Nauta Maaike H, Rapee Ronald M, Schneider Silvia, Schneider Sophie C, Silverman Wendy K, Thastum Mikael, Thirlwall Kerstin, Waite Polly, Wergeland Gro Janne, Breen Gerome, Eley Thalia C
Abstract excerpt
BACKGROUND: Anxiety disorders are common, and cognitive-behavioural therapy (CBT) is a first-line treatment. Candidate gene studies have suggested a genetic basis to treatment response, but findings have been inconsistent. AIMS: To perform the first genome-wide association study (GWAS) of psychological treatment response in children with anxiety disorders (n = 980). METHOD: Presence and severity of anxiety was...
Topics
- Adolescent
- Anxiety Disorders
- Child
- Child, Preschool
- Cognitive Behavioral Therapy
- Female
- Genome-Wide Association Study