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Article

Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression.

PloS one - 1 Jan 2015

Davies Matthew N, Verdi Serena, Burri Andrea, Trzaskowski Maciej, Lee Minyoung, Hettema John M, Jansen Rick, Boomsma Dorret I, Spector Tim D

Abstract excerpt

Generalised Anxiety Disorder (GAD) is a common anxiety-related diagnosis, affecting approximately 5% of the adult population. One characteristic of GAD is a high degree of anxiety sensitivity (AS), a personality trait which describes the fear of arousal-related sensations. Here we present a genome-wide association study of AS using a cohort of 730 MZ and DZ female twins. The GWAS showed a significant association...

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Identifiers

PMID: 26274327
DOI: 10.1371/journal.pone.0134865
PMCID: PMC4537268

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RBFOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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