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Article

Therapygenetics: anterior cingulate cortex-amygdala coupling is associated with 5-HTTLPR and treatment response in panic disorder with agoraphobia.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2015

Lueken Ulrike, Straube Benjamin, Wittchen Hans-Ulrich, Konrad Carsten, Ströhle Andreas, Wittmann André, Pfleiderer Bettina, Arolt Volker, Kircher Tilo, Deckert Jürgen, Reif Andreas

Abstract excerpt

Variation in the 5'-flanking promoter region of the serotonin transporter gene SLC6A4, the 5-HTT-linked polymorphic region (5-HTTLPR) has been inconclusively associated with response to cognitive-behavioural therapy (CBT). As genomic functions are stronger related to neural than to behavioural markers, we investigated the association of treatment response, 5-HTTLPR and functional brain connectivity in patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25223844
DOI: 10.1007/s00702-014-1311-2

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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