Genome-Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders.

doi:10.1002/ajmg.b.70015

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Article

Genome-Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Sept 2026

Bäckman Julia, Kravchenko Olly, Halvorsen Matthew, de Schipper Elles, Ivanova Ekaterina, Kaldo Viktor, Isacsson Nils Hentati, Eide Thorstein Olsen, Höffler Kira D, Mattheisen Manuel, Hansen Bjarne, Kvale Gerd, Hagen Kristen, Haavik Jan, Mataix-Cols David, Crowley James J, Wallert John, Rück Christian

Abstract excerpt

Cognitive behavioral therapy (CBT) is a well-established, evidence-based treatment for common mental disorders such as depression, anxiety disorders, and obsessive-compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement. Robust predictors of individual differences in symptom change are currently lacking. Genetic differences...

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PMID: 41804033
DOI: 10.1002/ajmg.b.70015

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