HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS.

doi:10.1002/da.22430

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Article

HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS.

Depression and anxiety - 1 Dec 2015

Roberts Susanna, Keers Robert, Lester Kathryn J, Coleman Jonathan R I, Breen Gerome, Arendt Kristian, Blatter-Meunier Judith, Cooper Peter, Creswell Cathy, Fjermestad Krister, Havik Odd E, Herren Chantal, Hogendoorn Sanne M, Hudson Jennifer L, Krause Karen, Lyneham Heidi J, Morris Talia, Nauta Maaike, Rapee Ronald M, Rey Yasmin, Schneider Silvia, Schneider Sophie C, Silverman Wendy K, Thastum Mikael, Thirlwall Kerstin, Waite Polly, Eley Thalia C, Wong Chloe C Y

Abstract excerpt

BACKGROUND: Hypothalamic-pituitary-adrenal (HPA) axis functioning has been implicated in the development of stress-related psychiatric diagnoses and response to adverse life experiences. This study aimed to investigate the association between genetic and epigenetics in HPA axis and response to cognitive behavior therapy (CBT). METHODS: Children with anxiety disorders were recruited into the Genes for Treatment...

Topics

Adolescent
Alleles
Anxiety Disorders
Child
Child, Preschool
Cognitive Behavioral Therapy
DNA Methylation
Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Epigenomics

Female

Humans

Hypothalamo-Hypophyseal System

Male

Pituitary-Adrenal System

Polymorphism, Single Nucleotide

Receptors, Glucocorticoid

Tacrolimus Binding Proteins

Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 26647360
DOI: 10.1002/da.22430
PMCID: PMC4982063

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26647360-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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