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Article

Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4.

Alcoholism, clinical and experimental research - 1 Aug 2016

Degenhardt Franziska, Krämer Laurenz, Frank Josef, Treutlein Jens, Heilmann-Heimbach Stefanie, Hecker Julian, Fier Heide Löhlein, Lang Maren, Witt Stephanie H, Koller Anna C, Mann Karl, Hoffmann Sabine, Kiefer Falk, Spanagel Rainer, Rietschel Marcella, Nöthen Markus M

Abstract excerpt

BACKGROUND: Common variants in the gene GATA binding protein 4 (GATA4) show association with alcohol dependence (AD). The aim of this study was to identify rare variants in GATA4 in order to elucidate the role of this gene in AD susceptibility. Identification of rare variants may provide a more complete picture of the allelic architecture at this risk locus. METHODS: Sanger sequencing of all 6 coding exons of...

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Source

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Identifiers

PMID: 27374936
DOI: 10.1111/acer.13125
PMCID: PMC5108491

Genes

GATA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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