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Article

Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence.

Alcoholism, clinical and experimental research - 1 Apr 2017

Clark Shaunna L, McClay Joseph L, Adkins Daniel E, Kumar Gaurav, Aberg Karolina A, Nerella Srilaxmi, Xie Linying, Collins Ann L, Crowley James J, Quackenbush Corey R, Hilliard Christopher E, Shabalin Andrey A, Vrieze Scott I, Peterson Roseann E, Copeland William E, Silberg Judy L, McGue Matt, Maes Hermine, Iacono William G, Sullivan Patrick F, Costello Elizabeth J, van den Oord Edwin J

Abstract excerpt

BACKGROUND: Previous genomewide association studies (GWASs) have identified a number of putative risk loci for alcohol dependence (AD). However, only a few loci have replicated and these replicated variants only explain a small proportion of AD risk. Using an innovative approach, the goal of this study was to generate hypotheses about potentially causal variants for AD that can be explored further through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28196272
DOI: 10.1111/acer.13352
PMCID: PMC5378639

Genes

ADHFE1
ADORA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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