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Article

Identification of Functional Genetic Variants Associated With Alcohol Dependence and Related Phenotypes Using a High-Throughput Assay.

Alcoholism, clinical and experimental research - 1 Dec 2020

Thapa Kriti S, Chen Andy B, Lai Dongbing, Xuei Xiaoling, Wetherill Leah, Tischfield Jay A, Liu Yunlong, Edenberg Howard J

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) of alcohol dependence (AD) and related phenotypes have identified multiple loci, but the functional variants underlying the loci have in most cases not been identified. Noncoding variants can influence phenotype by affecting gene expression; for example, variants in the 3' untranslated regions (3'UTR) can affect gene expression posttranscriptionally. METHODS: We...

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PMID: 33119910
DOI: 10.1111/acer.14492
PMCID: PMC7725989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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