Article
Selected polymorphisms of base excision repair genes and pancreatic cancer risk in Japanese.
Journal of epidemiology - 1 Jan 2012
Nakao Makoto, Hosono Satoyo, Ito Hidemi, Watanabe Miki, Mizuno Nobumasa, Sato Shigeki, Yatabe Yasushi, Yamao Kenji, Ueda Ryuzo, Tajima Kazuo, Tanaka Hideo, Matsuo Keitaro
Abstract excerpt
BACKGROUND: Although several reports have described a possible association between DNA repair genes and pancreatic cancer (PC) in smokers, this association has not been fully evaluated in an Asian population. We assessed the impact of genetic polymorphisms in the base excision repair (BER) pathway on PC risk among Japanese. METHODS: This case-control study compared the frequency of 5 single-nucleotide...
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