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Article

Association of DNA base-excision repair XRCC1, OGG1 and APE1 gene polymorphisms with nasopharyngeal carcinoma susceptibility in a Chinese population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Li Qing, Wang Jian-Min, Peng Yu, Zhang Shi-Heng, Ren Tao, Luo Hao, Cheng Yi, Wang Dong

Abstract excerpt

BACKGROUND: Numerous carcinogens and reactive oxygen species (ROS) may cause DNA damage including oxidative base lesions that lead to risk of nasopharyngeal carcinoma. Genetic susceptibility has been reported to play a key role in the development of this disease. The base excision repair (BER) pathway can effectively remove oxidative lesions, maintaining genomic stability and normal expression, with X-ray repair...

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Source

Identifiers

PMID: 24175791
DOI: 10.7314/apjcp.2013.14.9.5145

Genes

XRCC1
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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